The tables below records disorders known to involve hypertrichosis.
The first table lists disorders where hypertrichosis is a primary
symptom. The second table lists disorders where hypertrichosis
can be one of several symptoms. Typically the other symptoms are
of greater concern and health/life threatening.
The clinical distinction between hypertrichosis and hirsutism
is that hypertrichosis involves hair growth on any hair bearing
area of skin. The excess hair growth may induced by a wide variety
of environmental or genetic factors. Hirsutism is the growth of
hair in a secondary sexual characteristic pattern. In women hirsutism
involves unwanted excess hair limited to regions including the mustache,
beard, chest and/or escutcheon areas. Hirsutism is typically induced
by hormonal imbalance, especially androgen excess. This is not necessarily
a complete list of disorders involving hypertrichosis. Links to
relevant web pages on the Online
Mendelian Inheritance in Man (OMIM) web database are also given
where possible.
Where a disorder is known by more than one name, alternative
names are given in the second column and the record duplicated
in the first column under each respective name. Brackets around
alternative disorder names indicate an indirect association, for
example a subcategory of the disorder. These records are not duplicated
in the first column.
| Disorders with hypertrichosis as a primary symptom |
Alternative names for disorder |
Links to OMIM web pages for disorder (where available) |
| |
|
|
| Acquired localized hypertrichosis |
|
|
| Acquired hypertrichosis |
|
|
| Acquired generalized hypertrichosis |
|
|
| Ambras syndrome |
Congenital hypertrichosis universalis |
145701 |
| Anterior cervical hypertrichosis |
|
600457 |
| Becker nevus |
|
|
| Congenital generalized hypertrichosis |
|
307150 |
| Congenital hypertrichosis lanuginosa |
Hypertrichosis universalis |
145700 |
| Congenital hypertrichosis universalis |
Ambras syndrome |
145701 |
| Distichiasis |
(Two rows of eyelashes) |
126300 |
| Eyelash trichomegaly |
|
190330 |
| Facial hypertrichosis |
|
134000 |
| Faun tail |
|
|
| Hairy ears |
Hypertrichosis pinnae auris |
139500
425500 |
| Hairy elbows |
|
|
| Hypertrichosis pinnae auris |
Hairy ears |
139500
425500 |
| Hypertrichosis universalis |
Congenital hypertrichosis lanuginosa |
145700 |
| Pediatric hypertrichosis |
|
|
| Pigmented nevus |
|
|
| Trichomegaly |
(Two rows of eyelashes) |
190330 |
| Tristichiasis |
(Three rows of eyelashes) |
190800 |
| Disorders with hypertrichosis as a secondary symptom |
Alternative names for disorder |
Links to OMIM web pages for disorder (where available) |
| |
|
|
| Acrodynia |
|
|
| Autoimmune hyperthyroiditis |
Thyrotoxicosis,
Graves disease |
275000 |
| Biting induced hypertrichosis |
|
|
| Cancer |
(Various) |
List |
| CAtaract, Hypertrichosis, MEntal Retardation (CAHMER) syndrome |
|
211770 |
| Casts |
|
|
| Celiac disease |
|
212750 |
| Cervical hypertrichosis with underlying kyphoscoliosis |
|
117850 |
| Cherubism, gingival fibromatosis, epilepsy, mental deficiency,
hypertrichosis, and stunted growth |
Ramon syndrome |
266270 |
| Coffin-Siris syndrome |
Fifth digit syndrome |
135900 |
| Congenital A-V fistula |
(Various) |
List |
| Congenital smooth muscle hamartoma |
|
|
| Cornelia de Lange syndrome |
Typus degenerativus amstelodamensis
(De Lange syndrome,
Brachman-de Lange syndrome) |
122470 |
| Cowden syndrome |
Multiple hamartoma syndrome |
158350 |
| Denervation |
(Various) |
List |
| Diastematomyelia |
|
222500 |
| Donahue syndrome |
Leprechaunism |
246200 |
| Dwarfism |
(Various) |
List |
| Female pseudoturner syndrome |
Noonan syndrome,
Male turner syndrome |
163950 |
| Fetal Hydantoin syndrome |
(Epoxide hydrolase) |
132810 |
| Fetal Alcohol syndrome |
|
|
| Fifth digit syndrome |
Coffin-Siris syndrome |
135900 |
| Fucosidosis |
|
230000 |
| Gingival fibromatosis |
Hypertrichosis terminalis with gingival hyperplasia |
135300
135400
135500 |
| Globoid leukodystrophy |
Krabbe disease |
245200 |
| Gm1 gangliosidosis (Infantile Form) |
|
230500
230600 |
| Gorlin-Chaudhry-Moss syndrome |
|
233500 |
| Graves disease |
Thyrotoxicosis,
Autoimmune hyperthyroiditis |
275000 |
| Hamartoma |
|
|
| Holoprosencephaly |
(Various) |
List |
| Hurler syndrome |
|
252800 |
| Hyperkinetic circulatory disorder |
|
|
| Hypertrichosis lanuginosa |
Malignant down |
|
| Hypertrichosis terminalis with gingival hyperplasia |
Gingival fibromatosis |
135300
135400
135500 |
| Hypothyroidism |
(Various) |
List |
| Immunization |
|
|
| Klippel-Feil syndrome |
|
148900 |
| Krabbe disease |
Globoid leukodystrophy |
245200 |
| Lawerence-Seip syndrome |
(Seip syndrome) |
269700 |
| Lichen simplex chronicus |
|
|
| Lipoatrophic diabetes syndrome |
|
|
| Lipoma |
(Various) |
List |
| Mal de Meleda |
|
248300 |
| Male turner syndrome |
Noonan syndrome,
Female pseudoturner syndrome |
163950 |
| Malignant down |
Hypertrichosis lanuginosa |
|
| Marshall-Smith syndrome |
|
602535 |
| Melorheostatic scleroderma |
|
|
| Meningocele manque |
|
|
| Michelin tire baby syndrome |
|
156610 |
| Morphea |
|
|
| Mucopolysaccharidosis |
(Various) |
List |
| Multiple hamartoma syndrome |
Cowden syndrome |
158350 |
| Neoplasm |
(Various) |
List |
| Nevi pilorum |
|
|
| Noonan syndrome |
Male turner syndrome,
Female pseudoturner syndrome |
163950 |
| Neuroectodermal abnormalities |
(Various) |
List |
| Oliver-Macfarlane syndrome |
Trichomegaly with mental retardation, dwarfism, and pigmentary
degeneration of the retina |
275400 |
| Organ transplants |
|
|
| Osteochondrodysplasia |
|
239850 |
| Osteosclerotic myeloma |
|
|
| Pigmented hairy nevi |
|
|
| POEMS (Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal
protein, Skin changes) Porphyria |
|
|
| Porphyria |
|
176000
176010
176090
176100
176200
263700 |
| Pressure induced hypertrichosis |
|
|
| Ramon syndrome |
Cherubism, gingival fibromatosis, epilepsy, mental deficiency,
hypertrichosis, and stunted growth |
266270 |
| Rubinstein-Taybi syndrome |
|
180849 |
| Sanfilippo syndrome |
(Mucopolysaccharidosis) |
252900 |
| Schinzel-Giedon Syndrome |
|
269150 |
| Seckel syndrome |
Bird headed dwarfism |
210600 |
| Spina bifida |
|
182940 |
| Stiff skin syndrome |
|
184900 |
| Sunburn |
|
|
| Thyrotoxicosis |
Autoimmune hyperthyroiditis,
Graves disease |
275000 |
| Trauma induced hypertrichosis |
|
|
| Trichomegaly with mental retardation, dwarfism, and pigmentary
degeneration of the retina |
Oliver-Macfarlane syndrome |
275400 |
| Trisomy 18 |
|
601161 |
| Typus degenerativus amstelodamensis |
Cornelia de Lange syndrome
(De Lange syndrome,
Brachman-de Lange syndrome) |
122470 |
| Warburg micro syndrome |
|
600118 |
| Winchester syndrome |
|
277950 |
