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could a hormone imbalance be responsible for androgenetic alopecia ?

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Could a hormone imbalance be responsible for androgenetic alopecia

Yes sometimes. hormone imbalance can be involved in androgenetic alopecia. Women after menopause may have a net drop in the androgen antagonist estrogen and are much more susceptible to onset of pattern baldness. Other women can produce high levels of androgens making them more susceptible as occurs in polycystic ovary syndrome (PCOS) for example.

However, most androgenetic alopecia is idiopathic in nature. There is no detectable hormone imbalance causing the onset of hair loss and blood tests show nothing out of the ordinary. Because of this some dermatologists are very reluctant to treat androgenetic alopecia with hormone based treatments. They may regard such treatments as beyond their "domain" and more endocrinological than dermatological. This attitude is not helpful for those seeking treatment.

Some dermatologists, particularly in Europe, are more positive about using hormone therapies for pattern baldness in women. There are systemic antiandrogen treatments or hormone supplements available for women, but they are not generally suitable for men to use because of severe side effects. In the future some topical hormone treatments may also be available for men with androgenetic hair loss.


Could a hormone imbalance be responsible for androgenetic alopecia references

  • Zaun H, Ludwig E.Dermatologic indications for anti-androgenic treatment. Z Hautkr. 1978 Nov 1;53(21):759-65.
  • Orfanos CE, Vogels L. Local therapy of androgenetic alopecia with 17 alpha-estradiol. A controlled, randomized double-blind study. Dermatologica. 1980;161(2):124-32.
  • Schindler AE. Anti-androgen therapy in the female. Geburtshilfe Frauenheilkd. 1990 Oct;50(10):749-53.

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