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Drug
induced telogen effluvium
A form of telogen effluvium can develop when using certain prescription
and over the counter drugs. The mechanism by which drugs might
promote hair loss has not been investigated in detail, but it
is known that the hair loss is reversible and phenotypically looks
similar to telogen effluvium. Only a minority of people suffer
hair loss as a side effect from prescription drugs.
Any drugs you suspect might be involved in promoting hair loss
can be investigated using a physician's or pharmacist's desk reference
(PDR). These are comprehensive dictionaries listing approved prescription
drugs with their generic and trade names. These PDRs are issued
with relevance to your country of residence so PDRs issued in
different countries will list only those drugs approved for use
in that country. Note that trade names for drugs also differ from
country to country. These reference books should describe the
drugs, what they do, and any potential side effects. If hair loss
(or excess hair growth) has been found during drug trials or general
use then the effect should be listed in these references. A new
PDR is published each year and your doctor should have a current
version. Alternatively, you may find a PDR in your local library
and larger bookstores may also stock PDRs.
There are many, many drugs that can cause hair loss for just
one or two people in the hundreds of thousands that may use the
drug. We are each individuals with a unique genetic make up and
different environmental influences. This means that the same drug
can have subtly different effects on different people. Remember
that even when reference books record hair loss as a drug side
effect, it probably only occurred in a very small proportion of
the drug's users.
If you experience hair loss as a side effect of a drug and your
are resident in the USA your doctor can register your experience
with the Federal Drug administration (FDA) through the Adverse
Events Reporting System (AERS). See the The
FDA medical products reporting program (Medwatch) web site
for details.
Common
drugs causing telogen effluvium
For whatever reason, some drugs are more likely than others to
switch off hair follicle activity and lead to a diffuse form of
hair loss. The most common drug categories and examples of drugs
causing telogen effluvium type hair loss are listed below. This
is by no means an exhaustive list of drugs known to promote hair
loss.
- Cholesterol-lowering drugs, Clofibrate, Gemfibrozil
- Anti-hypertensive drugs, Diazoxide
- Anti-histamines/Ulcer drugs, Cimetidine, Ranitidine,
Famotidine
- Anti-coagulant drugs, Dicumarol, Heparin, Coumarin, Warfarin
- Anti-convulsant drugs, Ethotoin, Phenytoin, Mephenytoin,
Trimethadione, Paramethodione, Valproate sodium
- Anti-thyroid drugs, Carbimazole, Methimazole, Itriconazole,
Thiouracil
- Beta blockers/High blood pressure drugs, Acebutolol,
Nadolol, Atenolol, Pindolol, Labetalol, Metoprolol, Propranolol,
Timolol
- Non steroidal anti-inflammatory drugs, Aspirin, Fenoprofen,
Meclomen, Ibuprofen, Naproxen, Indomethacine, Piroxicam, Ketoprofen,
Sulindac
- Arthritis drugs, Penicillamine, Auranofin, Indomethacin,
Naproxen, Methotrexate
- Tricyclic anti-depressant drugs, Amitriptyline, Imipramine,
Amoxapine, Nortriptyline, Desipramine, Protriptyline, Doxepin,
Trimpramine
- Vitamin A derivative drugs, Retinoids, Retinol, Acitretin
, Isotretinoin, Etretinate, Vitamin A
- Miscallaneous drugs, Allopurinol, Aminodarone, Azothioprine,
Azulfidine, Bromocriptine, Carbamazepine, Choramphenicol, Clomiphene,
Clonidine, Colchicine, Dixyrazine, Ethambutol, Ethionamide, Etretianate,
Gentamycin, Haloperidol, Hydantoin, Levodopa, Interferon-alpha,
Methyldopa, Methysergide, Metyrapone, Nifrofurantoin, Para-amino-salicylic
acid, Prazosin, Probenecid, Pyridostigmine bromide, Sulphasalazine,
Terfenadine
Drug
induced telogen effluvium
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