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Kerion
A kerion is not an infectious agent in itself rather a kerion
is the skin leison that develops when an infectious agent that
normally
causes scalp ringworm (tinea capitis) becomes more aggressive.
Deep boggy red areas characterized
by a severe acute inflammatory infiltrate with pustule formation
are termed kerions or kerion celsi. Normally, scalp ringworm inducing
agents cause circular patches of red
crusty
skin. Although not pleasant, the problem is relatively mild
and reversible with proper treatment. However, if the infection
gets
out of hand
a kerion may develop.
Kerion
clinical features
When a kerion develops it first starts out as a more typical
presentation of tinea capitis with a flaky, crusty patch of skin
on the scalp. This can quickly deteriorate into a boggy, puritic
mass of inflamed tissue. This is a kerion. The kerion can deteriorate
to a nasty, deep abscess if it is not treated correctly. This
has the potential to to elicit scarring and permanent
alopecia. When a kerion develops with severe inflammation it is
fairly common for the regional lymph nodes in the neck to become
enlarged
(called
cervical
lymphadenopathy). Suppuration and kerion formation are more commonly
are typically associated with Trichophyton tonsurans infection.
Kerion formation with other infectious agents that cause tinea
capitis
are less
likely, but still possible.
Kerion
differential diagnosis
Sometimes Kerion Celsi is confused with other conditions due
to a lack of diagnostic testing. In one report, some patients
were
hospitalized with the diagnosis of Staphylococcal abscess
while a microbiological diagnostic test would have shown the
cause
was due to Trichophyton verrucosum infection resulting
in a kerion (Zaror, 1995). Occasionally, a kerion can look much
like
some forms of scarring alopecia such as dissecting cellulitis
or erosive pustular dermatosis. Because of this apparent similarity
in presentation, the doctor needs to be very careful in their
investigation
and knowledgeable about the potential for confusing kerions with
other diagnoses. The patient who suspects they have a kerion caused
by an infectious agent or something similar needs to find an experienced
dermatologist to
improve the chances of getting a correct diagnosis. The average
general practitioner is probably not in a position to make a kerion
diagnosis with confidence.
Kerion
treatment
Early initiation of treatment is extremely important with kerions.
The sooner treatment is started the less likely the kerion will
promote a permanent scarring alopecia. Unfortunately, some reports
suggest that rapid diagnosis and treatment of kerions only occurs
in a minority of cases or that kerions are often misdiagnosed.
There seems to be a certain lack of knowledge about tinea capitis
and
kerions among some general practitioners and this can lead to
a delay in receiving proper treatment. The longer kerions persist
the more damaging they become. When a kerion is diagnosed, the
typical
immediate treatment response is a course of "Griseofulvin",
an anti fungal agent. Most patients with kerions and a primary
diagnosis of tinea capitis also have a secondary bacterial infection
of the
kerion. Griseofulvin is not good for treating bacterial or yeast
infections so other anti-bacterial treatments may be given along
with the Griseofulvin. Some published case reports have indicated
the newer anti fungal agents Itraconazole and Terbinafine have
also been successfully used to treat kerions. Sometimes oral corticosteroids
are also given in addition to the anti fungal agent, although
the
few published studies comparing treatments with and without corticosteroids
have shown little added benefit. However in principle, oral corticosteroids
should help reduce the inflammation in the kerion. Topical corticosteroids
are not used as this can complicate the local fungal infection.
- Tanuma
H, Doi M, Abe M, Kume H, Nishiyama S, Katsuoka K. Case report.
Kerion Celsi effectively treated with terbinafine. Characteristics
of kerion Celsi in the elderly in Japan. Mycoses. 1999;42(9-10):581-5.
- Aste
N, Pau M, Biggio P. Kerion Celsi: a clinical epidemiological
study. Mycoses. 1998 Mar-Apr;41(3-4):169-73.
- Pomeranz
AJ, Fairley JA. Management errors leading to unnecessary hospitalization
for kerion. Pediatrics. 1994 Jun;93(6 Pt 1):986-8.
- Ginsburg
CM, Gan VN, Petruska M. Randomized controlled trial of intralesional
corticosteroid and griseofulvin vs. griseofulvin alone for treatment
of kerion. Pediatr Infect Dis J. 1987 Dec;6(12):1084-7.
- Calista D, Schianchi S, Morri M. Erythema
nodosum induced by kerion celsi of the scalp. Pediatr Dermatol.
2001 Mar-Apr;18(2):114-6.
- Kobayashi M, Yamamoto O, Suenaga Y, Asahi
M. Kerion celsi in an infant treated with oral terbinafine.
J Dermatol. 2001 Feb;28(2):108-9.
- Ive FA. Kerion formation caused by Trichophyton
rubrum. Br J Dermatol. 2000 May;142(5):1065-6.
- Hussain I, Muzaffar F, Rashid T, Ahmad
TJ, Jahangir M, Haroon TS. A randomized, comparative trial of
treatment of kerion celsi with griseofulvin plus oral prednisolone
vs. griseofulvin alone. Med Mycol. 1999 Apr;37(2):97-9.
- Beswick SJ, Das S, Lawrence CM, Tan BB.
Kerion formation due to Trichophyton rubrum. Br J Dermatol.
1999 Nov;141(5):953-4.
- Jury CS, Lucke TW, Bilsland D. Trichophyton
erinacei: an unusual cause of kerion. Br J Dermatol. 1999 Sep;141(3):606-7.
- Hussain I, Muzaffar F, Rashid T, Ahmad
TJ, Jahangir M, Haroon TS. A randomized, comparative trial of
treatment of kerion celsi with griseofulvin plus oral prednisolone
vs. griseofulvin alone. Med Mycol. 1999 Apr;37(2):97-9.
- Gupta G, Burden AD, Roberts DT. Acute
suppurative ringworm (kerion) caused by Trichophyton rubrum.
Br J Dermatol. 1999 Feb;140(2):369-70.
- Aste N, Pau M, Biggio P. Trichophyton
mentagrophytes kerion in a woman. Br J Dermatol. 1996 Dec;135(6):1010-1.
- Zaror L, Hering M, Moreno MI, Navarrete
M. [Kerion Celsi. A diagnostic problem? Experience with 6 cases]
Rev Med Chil. 1995 Aug;123(8):1006-8.
- Gordon PM, Stankler L. Rapid clearing
of kerion ringworm with terbinafine. Br J Dermatol. 1993 Oct;129(4):503-4.
- Honig PJ, Caputo GL, Leyden JJ, McGinley
K, Selbst SM, McGravey AR. Microbiology of kerions. J Pediatr.
1993 Sep;123(3):422-4.
- Gatti S, Marinaro C, Bianchi L, Nini
G. Treatment of kerion with fluconazole. Lancet. 1991 Nov 2;338(8775):1156.
- McDonagh AJ, Bleehen SS.Kerion masquerading
as erosive pustular dermatosis of the scalp. Br J Dermatol.
1991 May;124(5):507-8.
- Sperling LC. Inflammatory tinea capitis
(kerion) mimicking dissecting cellulitis. Occurrence in two
adolescents. Int J Dermatol. 1991 Mar;30(3):190-2.
- Franks AG, Rosenbaum EM, Mandel EH. Trichophyton
sulfureum causing erythema nodosum and multiple kerion formation.
Arch Dermatol Syphil 1952;65:95-97.
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